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Microtubule dynamics influence the retrograde biased motility of kinesin-4 motor teams in neuronal dendrites

Microtubules establish the directionality of intracellular transport by kinesins and dynein through polarized assembly, but it remains unclear how directed transport occurs along microtubules organized with mixed polarity. We investigated the ability of the plus end–directed kinesin-4 motor KIF21B t...

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Detalles Bibliográficos
Autores principales: Masucci, Erin M., Relich, Peter K., Lakadamyali, Melike, Ostap, E. Michael, Holzbaur, Erika L. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265162/
https://www.ncbi.nlm.nih.gov/pubmed/34705476
http://dx.doi.org/10.1091/mbc.E21-10-0480