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A multiparametric activity profiling platform for neuron disease phenotyping and drug screening

Patient stem cell–derived models enable imaging of complex disease phenotypes and the development of scalable drug discovery platforms. Current preclinical methods for assessing cellular activity do not, however, capture the full intricacies of disease-induced disturbances and instead typically focu...

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Detalles Bibliográficos
Autores principales: Boivin, Bruno, Roet, Kasper C. D., Huang, Xuan, Karhohs, Kyle W., Rohban, Mohammad H., Sandoe, Jack, Wiskow, Ole, Maeda, Rie, Grantham, Alyssa, Dornon, Mary K., Shao, Jenny, Frost, Devlin, Baker, Dylan, Eggan, Kevin, Carpenter, Anne E., Woolf, Clifford J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265164/
https://www.ncbi.nlm.nih.gov/pubmed/34910584
http://dx.doi.org/10.1091/mbc.E21-10-0481