Aqueous Extract of Descuraniae Semen Attenuates Lipopolysaccharide-Induced Inflammation and Apoptosis by Regulating the Proteasomal Degradation and IRE1α-Dependent Unfolded Protein Response in A549 Cells

BACKGROUND: Lipopolysaccharide (LPS)-induced acute lung injury (ALI) induces endoplasmic reticulum stress, unfolded protein response (UPR), apoptosis, and inflammation. Inositol-requiring enzyme 1 (IRE1)-α is important for adaptive and apoptotic UPR determination during ER stress. The aqueous extrac...

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Detalles Bibliográficos
Autores principales: Hsieh, Po-Chun, Peng, Chung-Kan, Liu, Guan-Ting, Kuo, Chan-Yen, Tzeng, I-Shiang, Wang, Ming-Chieh, Lan, Chou-Chin, Huang, Kun-Lun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265213/
https://www.ncbi.nlm.nih.gov/pubmed/35812413
http://dx.doi.org/10.3389/fimmu.2022.916102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265213/
https://www.ncbi.nlm.nih.gov/pubmed/35812413
http://dx.doi.org/10.3389/fimmu.2022.916102

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