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Standardization of Cell Culture Conditions and Routine Genomic Screening under a Quality Management System Leads to Reduced Genomic Instability in hPSCs

Human pluripotent stem cells (hPSCs) have generated unprecedented interest in the scientific community, given their potential applications in regenerative medicine, disease modeling, toxicology and drug screening. However, hPSCs are prone to acquire genomic alterations in vitro, mainly due to subopt...

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Detalles Bibliográficos
Autores principales: Molina-Ruiz, Francisco J., Introna, Clelia, Bombau, Georgina, Galofre, Mireia, Canals, Josep M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265327/
https://www.ncbi.nlm.nih.gov/pubmed/35805069
http://dx.doi.org/10.3390/cells11131984