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Standardization of Cell Culture Conditions and Routine Genomic Screening under a Quality Management System Leads to Reduced Genomic Instability in hPSCs
Human pluripotent stem cells (hPSCs) have generated unprecedented interest in the scientific community, given their potential applications in regenerative medicine, disease modeling, toxicology and drug screening. However, hPSCs are prone to acquire genomic alterations in vitro, mainly due to subopt...
Autores principales: | Molina-Ruiz, Francisco J., Introna, Clelia, Bombau, Georgina, Galofre, Mireia, Canals, Josep M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265327/ https://www.ncbi.nlm.nih.gov/pubmed/35805069 http://dx.doi.org/10.3390/cells11131984 |
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