Mitoribosomal Deregulation Drives Senescence via TPP1-Mediated Telomere Deprotection

While mitochondrial bioenergetic deregulation has long been implicated in cellular senescence, its mechanistic involvement remains unclear. By leveraging diverse mitochondria-related gene expression profiles derived from two different cellular senescence models of human diploid fibroblasts, we found...

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Detalles Bibliográficos
Autores principales: Min, Seongki, Kwon, So Mee, Hong, Jiwon, Lee, Young-Kyoung, Park, Tae Jun, Lim, Su Bin, Yoon, Gyesoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265344/
https://www.ncbi.nlm.nih.gov/pubmed/35805162
http://dx.doi.org/10.3390/cells11132079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265344/
https://www.ncbi.nlm.nih.gov/pubmed/35805162
http://dx.doi.org/10.3390/cells11132079

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