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Mitoribosomal Deregulation Drives Senescence via TPP1-Mediated Telomere Deprotection

While mitochondrial bioenergetic deregulation has long been implicated in cellular senescence, its mechanistic involvement remains unclear. By leveraging diverse mitochondria-related gene expression profiles derived from two different cellular senescence models of human diploid fibroblasts, we found...

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Detalles Bibliográficos
Autores principales:	Min, Seongki, Kwon, So Mee, Hong, Jiwon, Lee, Young-Kyoung, Park, Tae Jun, Lim, Su Bin, Yoon, Gyesoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265344/ https://www.ncbi.nlm.nih.gov/pubmed/35805162 http://dx.doi.org/10.3390/cells11132079

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