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Diverse Functions of KDM5 in Cancer: Transcriptional Repressor or Activator?

SIMPLE SUMMARY: Aberrations in epigenetic modulators have been widely identified in cancer; therefore, these modulators are attractive targets for cancer treatment. KDM5 is an H3K4 demethylase family that is recognized as a cancer-associated epigenetic regulator. However, the role of KDM5 and its tr...

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Detalles Bibliográficos
Autores principales: Ohguchi, Yasuyo, Ohguchi, Hiroto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265395/
https://www.ncbi.nlm.nih.gov/pubmed/35805040
http://dx.doi.org/10.3390/cancers14133270