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mTOR-Dependent Autophagy Regulates Slit Diaphragm Density in Podocyte-like Drosophila Nephrocytes

Both mTOR signaling and autophagy are important modulators of podocyte homeostasis, regeneration, and aging and have been implicated in glomerular diseases. However, the mechanistic role of these pathways for the glomerular filtration barrier remains poorly understood. We used Drosophila nephrocytes...

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Detalles Bibliográficos
Autores principales: Spitz, Dominik, Comas, Maria, Gerstner, Lea, Kayser, Séverine, Helmstädter, Martin, Walz, Gerd, Hermle, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265458/
https://www.ncbi.nlm.nih.gov/pubmed/35805186
http://dx.doi.org/10.3390/cells11132103