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Possible Metastatic Stage-Dependent ILC2 Activation Induces Differential Functions of MDSCs through IL-13/IL-13Rα1 Signaling during the Progression of Breast Cancer Lung Metastasis

SIMPLE SUMMARY: When breast cancer metastasizes to the lung, group 2 innate lymphoid cells (ILC2s) are thought to promote tumor growth via the activation of myeloid-derived suppressor cells (MDSCs). In this study, we aimed to characterize the dynamic interactions of ILC2s and MDSCs during the course...

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Detalles Bibliográficos
Autores principales: Ito, Atsushi, Akama, Yuichi, Satoh-Takayama, Naoko, Saito, Kanako, Kato, Takuma, Kawamoto, Eiji, Gaowa, Arong, Park, Eun Jeong, Takao, Motoshi, Shimaoka, Motomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265472/
https://www.ncbi.nlm.nih.gov/pubmed/35805039
http://dx.doi.org/10.3390/cancers14133267