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The Three Two-Pore Channel Subtypes from Rabbit Exhibit Distinct Sensitivity to Phosphoinositides, Voltage, and Extracytosolic pH

Two pore channels (TPCs) are implicated in vesicle trafficking, virus infection, and autophagy regulation. As Na(+)- or Ca(2+)-permeable channels, TPCs have been reported to be activated by NAADP, PI(3,5)P(2), and/or high voltage. However, a comparative study on the function and regulation of the th...

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Detalles Bibliográficos
Autores principales: Feng, Xinghua, Xiong, Jian, Cai, Weijie, Tian, Jin-Bin, Zhu, Michael X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265530/
https://www.ncbi.nlm.nih.gov/pubmed/35805090
http://dx.doi.org/10.3390/cells11132006