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Differences in Antioxidant and Lipid Handling Protein Expression Influence How Cells Expressing Distinct Mutant TP53 Subtypes Maintain Iron Homeostasis

The tumor suppressor TP53 is the most commonly mutated gene in human cancers, and iron is necessary for cancer cell growth and proliferation, but there is a significant gap in knowledge for how the two cooperate to affect cellular physiology. Elucidating this role is complicated, however, because ea...

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Detalles Bibliográficos
Autores principales: Cardona, Cameron J., Hermann, Evan R., Kouplen, Kate N., Hartson, Steven D., Montgomery, McKale R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265551/
https://www.ncbi.nlm.nih.gov/pubmed/35805147
http://dx.doi.org/10.3390/cells11132064