Integrin β3 Promotes Resistance to EGFR-TKI in Non-Small-Cell Lung Cancer by Upregulating AXL through the YAP Pathway

Integrin β3 plays a key role in the resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKI), but the development of integrin β3 inhibitors has been stalled due to the failure of phase III clinical trials for cancer treatment. Therefore, it is imperative to find a potenti...

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Detalles Bibliográficos
Autores principales: Sun, Qi, Lu, Zhihua, Zhang, Yanpeng, Xue, Dong, Xia, Huayu, She, Junjun, Li, Fanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265629/
https://www.ncbi.nlm.nih.gov/pubmed/35805163
http://dx.doi.org/10.3390/cells11132078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265629/
https://www.ncbi.nlm.nih.gov/pubmed/35805163
http://dx.doi.org/10.3390/cells11132078

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