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Integrin β3 Promotes Resistance to EGFR-TKI in Non-Small-Cell Lung Cancer by Upregulating AXL through the YAP Pathway
Integrin β3 plays a key role in the resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKI), but the development of integrin β3 inhibitors has been stalled due to the failure of phase III clinical trials for cancer treatment. Therefore, it is imperative to find a potenti...
Autores principales: | Sun, Qi, Lu, Zhihua, Zhang, Yanpeng, Xue, Dong, Xia, Huayu, She, Junjun, Li, Fanni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265629/ https://www.ncbi.nlm.nih.gov/pubmed/35805163 http://dx.doi.org/10.3390/cells11132078 |
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