A Signature of Exaggerated Adipose Tissue Dysfunction in Type 2 Diabetes Is Linked to Low Plasma Adiponectin and Increased Transcriptional Activation of Proteasomal Degradation in Muscle

Insulin resistance in skeletal muscle in type 2 diabetes (T2D) is characterized by more pronounced metabolic and molecular defects than in obesity per se. There is increasing evidence that adipose tissue dysfunction contributes to obesity-induced insulin resistance in skeletal muscle. Here, we used...

Descripción completa

Detalles Bibliográficos
Autores principales: Sabaratnam, Rugivan, Skov, Vibe, Paulsen, Søren K., Juhl, Stine, Kruse, Rikke, Hansen, Thea, Halkier, Cecilie, Kristensen, Jonas M., Vind, Birgitte F., Richelsen, Bjørn, Knudsen, Steen, Dahlgaard, Jesper, Beck-Nielsen, Henning, Kruse, Torben A., Højlund, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265693/
https://www.ncbi.nlm.nih.gov/pubmed/35805088
http://dx.doi.org/10.3390/cells11132005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265693/
https://www.ncbi.nlm.nih.gov/pubmed/35805088
http://dx.doi.org/10.3390/cells11132005

Ejemplares similares