LIM Kinases, Promising but Reluctant Therapeutic Targets: Chemistry and Preclinical Validation In Vivo

LIM Kinases are important actors in the regulation of cytoskeleton dynamics by controlling microtubule and actin filament turnover. The signaling pathways involving LIM kinases for actin filament remodeling are well established. They are downstream effectors of small G proteins of the Rho-GTPases fa...

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Detalles Bibliográficos
Autores principales: Berabez, Rayan, Routier, Sylvain, Bénédetti, Hélène, Plé, Karen, Vallée, Béatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265711/
https://www.ncbi.nlm.nih.gov/pubmed/35805176
http://dx.doi.org/10.3390/cells11132090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265711/
https://www.ncbi.nlm.nih.gov/pubmed/35805176
http://dx.doi.org/10.3390/cells11132090

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