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Cytoplasmic LMO2-LDB1 Complex Activates STAT3 Signaling through Interaction with gp130-JAK in Glioma Stem Cells

The oncogenic role of nuclear LIM domain only 2 (LMO2) as a transcriptional regulator is well established, but its function in the cytoplasm is largely unknown. Here, we identified LMO2 as a cytoplasmic activator for signal transducer and activator of transcription 3 (STAT3) signaling in glioma stem...

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Detalles Bibliográficos
Autores principales: Park, Cheol Gyu, Choi, Sang-Hun, Lee, Seon Yong, Eun, Kiyoung, Park, Min Gi, Jang, Junseok, Jeong, Hyeon Ju, Kim, Seong Jin, Jeong, Sohee, Lee, Kanghun, Kim, Hyunggee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265747/
https://www.ncbi.nlm.nih.gov/pubmed/35805116
http://dx.doi.org/10.3390/cells11132031