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Hypothalamic CREB Regulates the Expression of Pomc-Processing Enzyme Pcsk2

Background: The hypothalamic proopiomelanocortin (Pomc) neurons act as first-order sensors of systemic energy stores, providing signals that regulate caloric intake and energy expenditure. In experimental obesity, dietary saturated fatty acids affect Pomc endopeptidases (PCs), resulting in the abnor...

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Detalles Bibliográficos
Autores principales: Zanesco, Ariane Maria, Mendes, Natalia F., Engel, Daiane F., Gaspar, Rodrigo S., Sidarta-Oliveira, Davi, Donato, José, Velloso, Licio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265861/
https://www.ncbi.nlm.nih.gov/pubmed/35805082
http://dx.doi.org/10.3390/cells11131996