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EA.hy926 Cells and HUVECs Share Similar Senescence Phenotypes but Respond Differently to the Senolytic Drug ABT-263

Doxorubicin (DOX) induces endothelial cell (EC) senescence, which contributes to endothelial dysfunction and cardiovascular complications. Senolytic drugs selectively eliminate senescent cells to ameliorate senescence-mediated pathologies. Previous studies have demonstrated differences between immor...

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Detalles Bibliográficos
Autores principales: Abdelgawad, Ibrahim Y., Agostinucci, Kevin, Ismail, Somia G., Grant, Marianne K. O., Zordoky, Beshay N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266052/
https://www.ncbi.nlm.nih.gov/pubmed/35805077
http://dx.doi.org/10.3390/cells11131992