PFKM inhibits doxorubicin-induced cardiotoxicity by enhancing oxidative phosphorylation and glycolysis

Heart failure (HF) is a global pandemic which affects about 26 million people. PFKM (Phosphofructokinase, Muscle), catalyzing the phosphorylation of fructose-6-phosphate, plays a very important role in cardiovascular diseases. However, the effect of PFKM in glycolysis and HF remains to be elucidated...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Min, Sun, Xiao, Wang, Chunli, Wang, Fengdan, Fang, Chuibi, Hu, Zhenlei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266090/
https://www.ncbi.nlm.nih.gov/pubmed/35804014
http://dx.doi.org/10.1038/s41598-022-15743-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266090/
https://www.ncbi.nlm.nih.gov/pubmed/35804014
http://dx.doi.org/10.1038/s41598-022-15743-0

Ejemplares similares