Cargando…

PFKM inhibits doxorubicin-induced cardiotoxicity by enhancing oxidative phosphorylation and glycolysis

Heart failure (HF) is a global pandemic which affects about 26 million people. PFKM (Phosphofructokinase, Muscle), catalyzing the phosphorylation of fructose-6-phosphate, plays a very important role in cardiovascular diseases. However, the effect of PFKM in glycolysis and HF remains to be elucidated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Min, Sun, Xiao, Wang, Chunli, Wang, Fengdan, Fang, Chuibi, Hu, Zhenlei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266090/ https://www.ncbi.nlm.nih.gov/pubmed/35804014 http://dx.doi.org/10.1038/s41598-022-15743-0

Ejemplares similares

The role of S-nitrosylation of PFKM in regulation of glycolysis in ovarian cancer cells
por: Gao, Wenwen, et al.
Publicado: (2021)

ZEB1 enhances Warburg effect to facilitate tumorigenesis and metastasis of HCC by transcriptionally activating PFKM
por: Zhou, Yanming, et al.
Publicado: (2021)

Didymin attenuates doxorubicin-induced cardiotoxicity by inhibiting oxidative stress
por: Chen, Rongchang, et al.
Publicado: (2021)

Peroxiredoxin-1 Overexpression Attenuates Doxorubicin-Induced Cardiotoxicity by Inhibiting Oxidative Stress and Cardiomyocyte Apoptosis
por: Jiang, Lai, et al.
Publicado: (2020)

PFKM gene defect and glycogen storage disease GSDVII with misleading enzyme histochemistry
por: Auranen, Mari, et al.
Publicado: (2015)

Morphine Enhances Doxorubicin-Induced Cardiotoxicity in the Rat
por: Hole, Lisa Drange, et al.
Publicado: (2014)

Bone marrow mesenchymal stem cell-derived exosomal miR-21a-5p alleviates renal fibrosis by attenuating glycolysis by targeting PFKM
por: Xu, Shihao, et al.
Publicado: (2022)

PKM2 coordinates glycolysis with mitochondrial fusion and oxidative phosphorylation
por: Li, Tong, et al.
Publicado: (2019)

UVRAG Deficiency Exacerbates Doxorubicin-Induced Cardiotoxicity
por: An, Lin, et al.
Publicado: (2017)

Importance of glycolysis and oxidative phosphorylation in advanced melanoma
por: Ho, Jonhan, et al.
Publicado: (2012)

Resolvin D1 Attenuates Doxorubicin-Induced Cardiotoxicity by Inhibiting Inflammation, Oxidative and Endoplasmic Reticulum Stress
por: Wang, Menglong, et al.
Publicado: (2022)

Resveratrol solid lipid nanoparticles to trigger credible inhibition of doxorubicin cardiotoxicity
por: Zhang, Lili, et al.
Publicado: (2019)

INKing the Cardiotoxicity Out of Doxorubicin
por: Guo, Zhen, et al.
Publicado: (2023)

The Role of Nitric Oxide in Doxorubicin-Induced Cardiotoxicity: Experimental Study
por: Bahadır, Ayşenur, et al.
Publicado: (2014)

Role of acetylation in doxorubicin-induced cardiotoxicity
por: Li, Daisong, et al.
Publicado: (2021)

Cinnamaldehyde alleviates doxorubicin-induced cardiotoxicity by decreasing oxidative stress and ferroptosis in cardiomyocytes
por: Mao, Meijiao, et al.
Publicado: (2023)

Biochanin A Inhibits Glioblastoma Growth via Restricting Glycolysis and Mitochondrial Oxidative Phosphorylation
por: Dong, Qiang, et al.
Publicado: (2021)

Ssc-miR-92b-3p Regulates Porcine Trophoblast Cell Proliferation and Migration via the PFKM Gene
por: Wang, Yongzhong, et al.
Publicado: (2022)

The true colors of autophagy in doxorubicin-induced cardiotoxicity
por: Xiao, Bin, et al.
Publicado: (2019)

Combat Doxorubicin Cardiotoxicity With the Power of Mitochondria Transfer
por: Wang, Dennis D., et al.
Publicado: (2021)

Bibliometric and visual analysis of doxorubicin-induced cardiotoxicity
por: Lin, Xiaoxiao, et al.
Publicado: (2023)

Protection against Doxorubicin-Induced Cardiotoxicity by Ergothioneine
por: Cheah, Irwin K., et al.
Publicado: (2023)

First description of phosphofructokinase deficiency in spain: identification of a novel homozygous missense mutation in the PFKM gene
por: Vives-Corrons, Joan-Lluis, et al.
Publicado: (2013)

Dipyridamole ameliorates doxorubicin-induced cardiotoxicity
por: Alyasiry, Esraa, et al.
Publicado: (2022)

Peptidomics Analysis Reveals Peptide PDCryab1 Inhibits Doxorubicin-Induced Cardiotoxicity
por: Zhang, Li, et al.
Publicado: (2020)

Hyperhomocysteinaemia Promotes Doxorubicin-Induced Cardiotoxicity in Mice
por: Fan, Rui, et al.
Publicado: (2023)

Osteocrin attenuates inflammation, oxidative stress, apoptosis, and cardiac dysfunction in doxorubicin‐induced cardiotoxicity
por: Hu, Can, et al.
Publicado: (2020)

The beneficial role of exercise in preventing doxorubicin-induced cardiotoxicity
por: Gaytan, Samantha L., et al.
Publicado: (2023)

WGX50 mitigates doxorubicin-induced cardiotoxicity through inhibition of mitochondrial ROS and ferroptosis
por: Tai, Panpan, et al.
Publicado: (2023)

MicroRNA-383-5p Regulates Oxidative Stress in Mice with Acute Myocardial Infarction through the AMPK Signaling Pathway via PFKM
por: Gao, Linlin, et al.
Publicado: (2021)

Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin
por: DeWaal, Dannielle, et al.
Publicado: (2018)

Effect of fermented Cordyceps sinensis on doxorubicin-induced cardiotoxicity in rats
por: Wu, Rong, et al.
Publicado: (2018)

Isorhamnetin Protects against Doxorubicin-Induced Cardiotoxicity In Vivo and In Vitro
por: Sun, Jing, et al.
Publicado: (2013)

Expression of HK2, PKM2, and PFKM Is Associated with Metastasis and Late Disease Onset in Breast Cancer Patients
por: Ishfaq, Mehreen, et al.
Publicado: (2022)

MicroRNA in the Diagnosis and Treatment of Doxorubicin-Induced Cardiotoxicity
por: Kuang, Ziyu, et al.
Publicado: (2023)

Enhancing oxidative phosphorylation over glycolysis for energy production in cultured mesenchymal stem cells
por: Monsour, Molly, et al.
Publicado: (2022)

Methyl Gallate Attenuates Doxorubicin-Induced Cardiotoxicity in Rats by Suppressing Oxidative Stress
por: Ahmed, Akheruz Zaman, et al.
Publicado: (2021)

Underlying the Mechanisms of Doxorubicin-Induced Acute Cardiotoxicity: Oxidative Stress and Cell Death
por: Kong, Chun-Yan, et al.
Publicado: (2022)

Inhibition of TRPA1 Attenuates Doxorubicin-Induced Acute Cardiotoxicity by Suppressing Oxidative Stress, the Inflammatory Response, and Endoplasmic Reticulum Stress
por: Wang, Zhen, et al.
Publicado: (2018)

Ginsenoside Rg3 micelles mitigate doxorubicin-induced cardiotoxicity and enhance its anticancer efficacy
por: Li, Lan, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_a7jolqefm8qrd99vbvs2lglho9