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Suppressing VEGF-A/VEGFR-2 Signaling Contributes to the Anti-Angiogenic Effects of PPE8, a Novel Naphthoquinone-Based Compound

Natural naphthoquinones and their derivatives exhibit a broad spectrum of pharmacological activities and have thus attracted much attention in modern drug discovery. However, it remains unclear whether naphthoquinones are potential drug candidates for anti-angiogenic agents. The aim of this study wa...

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Detalles Bibliográficos
Autores principales: Hsu, Ming-Jen, Chen, Han-Kun, Lien, Jin-Cherng, Huang, Yu-Han, Huang, Shiu-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266117/
https://www.ncbi.nlm.nih.gov/pubmed/35805198
http://dx.doi.org/10.3390/cells11132114