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Elevated NF-κB/SHh/GLI1 Signature Denotes a Worse Prognosis and Represent a Novel Potential Therapeutic Target in Advanced Prostate Cancer

Prostate cancer (PCa) is the second most frequent cancer in men worldwide. NF-κB seems to play a key role in cell survival, proliferation and invasion, sustaining the heterogeneous multifocal nature of PCa. In recent years, the Hedgehog (Hh) signaling pathway has attracted attention as a therapeutic...

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Detalles Bibliográficos
Autores principales: Vecchiotti, Davide, Verzella, Daniela, Di Vito Nolfi, Mauro, D’Andrea, Daniel, Flati, Irene, Di Francesco, Barbara, Cornice, Jessica, Alesse, Edoardo, Capece, Daria, Zazzeroni, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266159/
https://www.ncbi.nlm.nih.gov/pubmed/35805202
http://dx.doi.org/10.3390/cells11132118