PKC-Mediated Orai1 Channel Phosphorylation Modulates Ca(2+) Signaling in HeLa Cells

The overexpression of the Orai1 channel inhibits SOCE when using the Ca(2+) readdition protocol. However, we found that HeLa cells overexpressing the Orai1 channel displayed enhanced Ca(2+) entry and a limited ER depletion in response to the combination of ATP and thapsigargin (TG) in the presence o...

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Detalles Bibliográficos
Autores principales: Martínez-Martínez, Ericka, Sánchez-Vázquez, Víctor Hugo, León-Aparicio, Daniel, Sanchez-Collado, Jose, Gallegos-Gómez, Martín-Leonardo, Rosado, Juan A., Arias, Juan M., Guerrero-Hernández, Agustin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266177/
https://www.ncbi.nlm.nih.gov/pubmed/35805121
http://dx.doi.org/10.3390/cells11132037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266177/
https://www.ncbi.nlm.nih.gov/pubmed/35805121
http://dx.doi.org/10.3390/cells11132037

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