11β-Hydroxysteroid Dehydrogenase Type 1 within Osteoclasts Mediates the Bone Protective Properties of Therapeutic Corticosteroids in Chronic Inflammation

Therapeutic glucocorticoids (GCs) are powerful anti-inflammatory tools in the management of chronic inflammatory diseases such as rheumatoid arthritis (RA). However, their actions on bone in this context are complex. The enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) is a mediator of the...

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Detalles Bibliográficos
Autores principales: Fenton, Chloe G, Crastin, Ana, Martin, Claire S, Suresh, Saicharan, Montagna, Isabella, Hussain, Bismah, Naylor, Amy J, Jones, Simon W, Hansen, Morten S, Gorvin, Caroline M, Price, Maria, Filer, Andrew, Cooper, Mark S, Lavery, Gareth G, Raza, Karim, Hardy, Rowan S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266304/
https://www.ncbi.nlm.nih.gov/pubmed/35806338
http://dx.doi.org/10.3390/ijms23137334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266304/
https://www.ncbi.nlm.nih.gov/pubmed/35806338
http://dx.doi.org/10.3390/ijms23137334

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