Phosphomimicry on STAU1 Serine 20 Impairs STAU1 Posttranscriptional Functions and Induces Apoptosis in Human Transformed Cells

Staufen 1 (STAU1) is an RNA-binding protein that is essential in untransformed cells. In cancer cells, it is rather STAU1 overexpression that impairs cell proliferation. In this paper, we show that a modest increase in STAU1 expression in cancer cells triggers apoptosis as early as 12 h post-transfe...

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Detalles Bibliográficos
Autores principales: Gonzalez Quesada, Yulemi, Bonnet-Magnaval, Florence, DesGroseillers, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266326/
https://www.ncbi.nlm.nih.gov/pubmed/35806349
http://dx.doi.org/10.3390/ijms23137344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266326/
https://www.ncbi.nlm.nih.gov/pubmed/35806349
http://dx.doi.org/10.3390/ijms23137344

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