Metformin Attenuates UVA-Induced Skin Photoaging by Suppressing Mitophagy and the PI3K/AKT/mTOR Pathway

Ultraviolet (UV) radiation is a major cause of photoaging that can induce DNA damage, oxidative stress, and cellular aging. Metformin (MF) can repair DNA damage, scavenge reactive oxygen species (ROS), and protect cells. However, the mechanism by which MF inhibits cell senescence in chronic skin dam...

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Detalles Bibliográficos
Autores principales: Chen, Qiuyan, Zhang, Haiying, Yang, Yimeng, Zhang, Shuming, Wang, Jing, Zhang, Dawei, Yu, Huimei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266365/
https://www.ncbi.nlm.nih.gov/pubmed/35805987
http://dx.doi.org/10.3390/ijms23136960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266365/
https://www.ncbi.nlm.nih.gov/pubmed/35805987
http://dx.doi.org/10.3390/ijms23136960

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