Synthesis and Biological Evaluation of Small Molecules as Potential Anticancer Multitarget Agents

Twenty-six triazole-based derivatives were designed for targeting both PD-L1 (programmed death receptor ligand 1) and VEGFR-2 (vascular endothelial growth factor receptor 2). These compounds were synthetized and biologically evaluated as multitarget inhibitors of VEGFR-2, PD-L1 and c-Myc proteins. T...

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Detalles Bibliográficos
Autores principales: Pla-López, Alberto, Castillo, Raquel, Cejudo-Marín, Rocío, García-Pedrero, Olaya, Bakir-Laso, Mariam, Falomir, Eva, Carda, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266368/
https://www.ncbi.nlm.nih.gov/pubmed/35806053
http://dx.doi.org/10.3390/ijms23137049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266368/
https://www.ncbi.nlm.nih.gov/pubmed/35806053
http://dx.doi.org/10.3390/ijms23137049

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