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Chronically Radiation-Exposed Survivor Glioblastoma Cells Display Poor Response to Chk1 Inhibition under Hypoxia

Glioblastoma is the most malignant primary brain tumor, and a cornerstone in its treatment is radiotherapy. However, tumor cells surviving after irradiation indicates treatment failure; therefore, better understanding of the mechanisms regulating radiotherapy response is of utmost importance. In thi...

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Detalles Bibliográficos
Autores principales: Pinarbasi-Degirmenci, Nareg, Sur-Erdem, Ilknur, Akcay, Vuslat, Bolukbasi, Yasemin, Selek, Ugur, Solaroglu, Ihsan, Bagci-Onder, Tugba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266388/
https://www.ncbi.nlm.nih.gov/pubmed/35806055
http://dx.doi.org/10.3390/ijms23137051