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LRF Promotes Indirectly Advantageous Chromatin Conformation via BGLT3-lncRNA Expression and Switch from Fetal to Adult Hemoglobin

The hemoglobin switch from fetal (HbF) to adult (HbA) has been studied intensively as an essential model for gene expression regulation, but also as a beneficial therapeutic approach for β-hemoglobinopathies, towards the objective of reactivating HbF. The transcription factor LRF (Leukemia/lymphoma-...

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Detalles Bibliográficos
Autores principales: Chondrou, Vasiliki, Shaukat, Athanasios-Nasir, Psarias, Georgios, Athanasopoulou, Katerina, Iliopoulou, Evanthia, Damanaki, Ariadne, Stathopoulos, Constantinos, Sgourou, Argyro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266405/
https://www.ncbi.nlm.nih.gov/pubmed/35806029
http://dx.doi.org/10.3390/ijms23137025