Variation of Structural and Dynamical Flexibility of Myelin Basic Protein in Response to Guanidinium Chloride

Myelin basic protein (MBP) is intrinsically disordered in solution and is considered as a conformationally flexible biomacromolecule. Here, we present a study on perturbation of MBP structure and dynamics by the denaturant guanidinium chloride (GndCl) using small-angle scattering and neutron spin–ec...

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Detalles Bibliográficos
Autores principales: Haris, Luman, Biehl, Ralf, Dulle, Martin, Radulescu, Aurel, Holderer, Olaf, Hoffmann, Ingo, Stadler, Andreas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266411/
https://www.ncbi.nlm.nih.gov/pubmed/35805997
http://dx.doi.org/10.3390/ijms23136969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266411/
https://www.ncbi.nlm.nih.gov/pubmed/35805997
http://dx.doi.org/10.3390/ijms23136969

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