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Human PARP1 Facilitates Transcription through a Nucleosome and Histone Displacement by Pol II In Vitro

Human poly(ADP)-ribose polymerase-1 (PARP1) is a global regulator of various cellular processes, from DNA repair to gene expression. The underlying mechanism of PARP1 action during transcription remains unclear. Herein, we have studied the role of human PARP1 during transcription through nucleosomes...

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Detalles Bibliográficos
Autores principales: Kotova, Elena Y., Hsieh, Fu-Kai, Chang, Han-Wen, Maluchenko, Natalia V., Langelier, Marie-France, Pascal, John M., Luse, Donal S., Feofanov, Alexey V., Studitsky, Vasily M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266421/
https://www.ncbi.nlm.nih.gov/pubmed/35806109
http://dx.doi.org/10.3390/ijms23137107