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Human PARP1 Facilitates Transcription through a Nucleosome and Histone Displacement by Pol II In Vitro
Human poly(ADP)-ribose polymerase-1 (PARP1) is a global regulator of various cellular processes, from DNA repair to gene expression. The underlying mechanism of PARP1 action during transcription remains unclear. Herein, we have studied the role of human PARP1 during transcription through nucleosomes...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266421/ https://www.ncbi.nlm.nih.gov/pubmed/35806109 http://dx.doi.org/10.3390/ijms23137107 |