Dried Blood Spots as Matrix for Evaluation of Valproate Levels and the Immediate and Delayed Metabolomic Changes Induced by Single Valproate Dose Treatment

The immediate and delayed metabolic changes in rats treated with valproate (VPA), a drug used for the treatment of epilepsy, were profiled. An established approach using dried blood spots (DBS) as sample matrices for gas chromatography/mass spectrometry-based metabolomics profiling was modified usin...

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Detalles Bibliográficos
Autores principales: Kong, Sing Teang, Lin, Hai-Shu, Ching, Jianhong, Xie, Huiqing, Ho, Paul C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266449/
https://www.ncbi.nlm.nih.gov/pubmed/35806086
http://dx.doi.org/10.3390/ijms23137083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266449/
https://www.ncbi.nlm.nih.gov/pubmed/35806086
http://dx.doi.org/10.3390/ijms23137083

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