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Effect of KRAS mutations and p53 expression on the postoperative prognosis of patients with colorectal cancer

BACKGROUND: In the occurrence and development of colorectal cancer, p53 is an important regulator downstream of the MAPK signaling pathway and plays an important role in inhibiting abnormal proliferation signals generated by KRAS mutations. The purpose of this study is to explore the correlation bet...

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Detalles Bibliográficos
Autores principales: Wang, Lingfeng, Lin, Shengtao, Yang, Changshun, Cai, Shaoxin, Li, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266597/
https://www.ncbi.nlm.nih.gov/pubmed/35686701
http://dx.doi.org/10.1002/mgg3.1905