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Triiodothyronine Acts as a Smart Influencer on Hsp90 via a Triiodothyronine Binding Site

Microarray-based experiments revealed that thyroid hormone triiodothyronine (T3) enhanced the binding of Cy5-labeled ATP on heat shock protein 90 (Hsp90). By molecular docking experiments with T3 on Hsp90, we identified a T3 binding site (TBS) near the ATP binding site on Hsp90. A synthetic peptide...

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Detalles Bibliográficos
Autores principales: Fan, Lu, Warnecke, Athanasia, Weder, Julia, Preller, Matthias, Zeilinger, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266618/
https://www.ncbi.nlm.nih.gov/pubmed/35806154
http://dx.doi.org/10.3390/ijms23137150