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Triiodothyronine Acts as a Smart Influencer on Hsp90 via a Triiodothyronine Binding Site
Microarray-based experiments revealed that thyroid hormone triiodothyronine (T3) enhanced the binding of Cy5-labeled ATP on heat shock protein 90 (Hsp90). By molecular docking experiments with T3 on Hsp90, we identified a T3 binding site (TBS) near the ATP binding site on Hsp90. A synthetic peptide...
Autores principales: | Fan, Lu, Warnecke, Athanasia, Weder, Julia, Preller, Matthias, Zeilinger, Carsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266618/ https://www.ncbi.nlm.nih.gov/pubmed/35806154 http://dx.doi.org/10.3390/ijms23137150 |
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