Methylphenidate Restores Behavioral and Neuroplasticity Impairments in the Prenatal Nicotine Exposure Mouse Model of ADHD: Evidence for Involvement of AMPA Receptor Subunit Composition and Synaptic Spine Morphology in the Hippocampus

In ADHD treatment, methylphenidate (MPH) is the most frequently used medication. The present work provides evidence that MPH restored behavioral impairments and neuroplasticity due to changes in AMPAR subunit composition and distribution, as well as maturation of dendritic spines, in a prenatal nico...

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Detalles Bibliográficos
Autores principales: Contreras, Darwin, Piña, Ricardo, Carvallo, Claudia, Godoy, Felipe, Ugarte, Gonzalo, Zeise, Marc, Rozas, Carlos, Morales, Bernardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266648/
https://www.ncbi.nlm.nih.gov/pubmed/35806103
http://dx.doi.org/10.3390/ijms23137099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266648/
https://www.ncbi.nlm.nih.gov/pubmed/35806103
http://dx.doi.org/10.3390/ijms23137099

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