Cargando…
Methylphenidate Restores Behavioral and Neuroplasticity Impairments in the Prenatal Nicotine Exposure Mouse Model of ADHD: Evidence for Involvement of AMPA Receptor Subunit Composition and Synaptic Spine Morphology in the Hippocampus
In ADHD treatment, methylphenidate (MPH) is the most frequently used medication. The present work provides evidence that MPH restored behavioral impairments and neuroplasticity due to changes in AMPAR subunit composition and distribution, as well as maturation of dendritic spines, in a prenatal nico...
Autores principales: | Contreras, Darwin, Piña, Ricardo, Carvallo, Claudia, Godoy, Felipe, Ugarte, Gonzalo, Zeise, Marc, Rozas, Carlos, Morales, Bernardo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266648/ https://www.ncbi.nlm.nih.gov/pubmed/35806103 http://dx.doi.org/10.3390/ijms23137099 |
Ejemplares similares
-
Single and Repeated Administration of Methylphenidate Modulates Synaptic Plasticity in Opposite Directions via Insertion of AMPA Receptors in Rat Hippocampal Neurons
por: Carvallo, Claudia, et al.
Publicado: (2018) -
Attention Deficit-Hyperactivity Disorder (ADHD): From Abnormal Behavior to Impairment in Synaptic Plasticity
por: Ugarte, Gonzalo, et al.
Publicado: (2023) -
AMPA Receptor Activation Causes Silencing of AMPA Receptor-Mediated Synaptic Transmission in the Developing Hippocampus
por: Wasling, Pontus, et al.
Publicado: (2012) -
ADHD, Methylphenidate, and Childhood Epilepsy
por: Sharma, Rahul, et al.
Publicado: (2016) -
The Risk of Methylphenidate Pharmacotherapy for Adults with ADHD
por: Bieś, Rafał, et al.
Publicado: (2023)