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Photorhabdus luminescens TccC3 Toxin Targets the Dynamic Population of F-Actin and Impairs Cell Cortex Integrity

Due to its essential role in cellular processes, actin is a common target for bacterial toxins. One such toxin, TccC3, is an effector domain of the ABC-toxin produced by entomopathogenic bacteria of Photorhabdus spp. Unlike other actin-targeting toxins, TccC3 uniquely ADP-ribosylates actin at Thr-14...

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Detalles Bibliográficos
Autores principales: Dong, Songyu, Zheng, Weili, Pinkerton, Nicholas, Hansen, Jacob, Tikunova, Svetlana B., Davis, Jonathan P., Heissler, Sarah M., Kudryashova, Elena, Egelman, Edward H., Kudryashov, Dmitri S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266650/
https://www.ncbi.nlm.nih.gov/pubmed/35806028
http://dx.doi.org/10.3390/ijms23137026