Silencing of the Ca(2+) Channel ORAI1 Improves the Multi-Systemic Phenotype of Tubular Aggregate Myopathy (TAM) and Stormorken Syndrome (STRMK) in Mice

Tubular aggregate myopathy (TAM) and Stormorken syndrome (STRMK) form a clinical continuum associating progressive muscle weakness with additional multi-systemic anomalies of the bones, skin, spleen, and platelets. TAM/STRMK arises from excessive extracellular Ca(2+) entry due to gain-of-function mu...

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Detalles Bibliográficos
Autores principales: Silva-Rojas, Roberto, Pérez-Guàrdia, Laura, Lafabrie, Emma, Moulaert, David, Laporte, Jocelyn, Böhm, Johann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266658/
https://www.ncbi.nlm.nih.gov/pubmed/35805973
http://dx.doi.org/10.3390/ijms23136968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266658/
https://www.ncbi.nlm.nih.gov/pubmed/35805973
http://dx.doi.org/10.3390/ijms23136968

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