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Glycation of Tie-2 Inhibits Angiopoietin-1 Signaling Activation and Angiopoietin-1-Induced Angiogenesis

The impairment of the angiopoietin-1 (Ang-1)/Tie-2 signaling pathway has been thought to play a critical role in diabetic complications. However, the underlying mechanisms remain unclear. The present study aims to investigate the effects of Tie-2 glycation on Ang-1 signaling activation and Ang-1-ind...

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Detalles Bibliográficos
Autores principales: Zhou, Haiyan, Chen, Tangting, Li, Yongjie, You, Jingcan, Deng, Xin, Chen, Ni, Li, Tian, Zheng, Youkun, Li, Rong, Luo, Mao, Wu, Jianbo, Wang, Liqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266685/
https://www.ncbi.nlm.nih.gov/pubmed/35806141
http://dx.doi.org/10.3390/ijms23137137