Cargando…

Glycation of Tie-2 Inhibits Angiopoietin-1 Signaling Activation and Angiopoietin-1-Induced Angiogenesis

The impairment of the angiopoietin-1 (Ang-1)/Tie-2 signaling pathway has been thought to play a critical role in diabetic complications. However, the underlying mechanisms remain unclear. The present study aims to investigate the effects of Tie-2 glycation on Ang-1 signaling activation and Ang-1-ind...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Haiyan, Chen, Tangting, Li, Yongjie, You, Jingcan, Deng, Xin, Chen, Ni, Li, Tian, Zheng, Youkun, Li, Rong, Luo, Mao, Wu, Jianbo, Wang, Liqun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266685/ https://www.ncbi.nlm.nih.gov/pubmed/35806141 http://dx.doi.org/10.3390/ijms23137137

Ejemplares similares

Advanced Glycation End-Products and Hyperglycemia Increase Angiopoietin-2 Production by Impairing Angiopoietin-1-Tie-2 System
por: Puddu, Alessandra, et al.
Publicado: (2019)

Prognostic significance of the angiopoietin-2/angiopoietin-1 and angiopoietin-1/Tie-2 ratios for early sepsis in an emergency department
por: Fang, Yingying, et al.
Publicado: (2015)

Glycation of fibronectin inhibits VEGF‐induced angiogenesis by uncoupling VEGF receptor‐2‐c‐Src crosstalk
por: Chen, Tangting, et al.
Publicado: (2020)

Expressions and Clinical Significances of Angiopoietin-1, Angiopoietin-2, and Tie-2 Receptor in Patients With Colorectal Cancer
por: Hong, Sunghoon, et al.
Publicado: (2017)

Role of the angiopoietin/Tie system in pregnancy (Review)
por: KAPPOU, D., et al.
Publicado: (2015)

Angiopoietin–Tie signalling in the cardiovascular and lymphatic systems
por: Eklund, Lauri, et al.
Publicado: (2016)

Expression of Angiopoietin-TIE System Components in Angiosarcoma
por: Buehler, Darya, et al.
Publicado: (2013)

Role of Angiopoietins and Tie-2 in Diabetic Retinopathy
por: Khalaf, Nervana, et al.
Publicado: (2017)

The Angiopoietin/Tie2 Pathway in Hepatocellular Carcinoma
por: Vanderborght, Bart, et al.
Publicado: (2020)

Angiopoietin-2 impairs collateral artery growth associated with the suppression of the infiltration of macrophages in mouse hindlimb ischaemia
por: Tan, Xiaoyong, et al.
Publicado: (2016)

Association of serum angiopoietin-1, angiopoietin-2 and angiopoietin-2 to angiopoietin-1 ratio with heart failure in patients with acute myocardial infarction
por: CHEN, SHAOMIN, et al.
Publicado: (2013)

Expression of Angiopoietin 1, 2 and Their Common Receptor Tie2 in Human Gastric Carcinoma: Implication for Angiogenesis
por: Moon, Woo Sung, et al.
Publicado: (2006)

Dysregulation of the angiopoietin–Tie-2 axis in sepsis and ARDS
por: Parikh, Samir M
Publicado: (2013)

The angiopoietin receptor Tie2 is atheroprotective in arterial endothelium
por: Anisimov, Andrey, et al.
Publicado: (2023)

Constitutive Association of Tie1 and Tie2 with Endothelial Integrins is Functionally Modulated by Angiopoietin-1 and Fibronectin
por: Dalton, Annamarie C., et al.
Publicado: (2016)

MG53 inhibits angiogenesis through regulating focal adhesion kinase signalling
por: Dong, Jinling, et al.
Publicado: (2021)

Correction: Constitutive Association of Tie1 and Tie2 with Endothelial Integrins is Functionally Modulated by Angiopoietin-1 and Fibronectin
por: Dalton, Annamarie C., et al.
Publicado: (2017)

Tie2-Dependent Neovascularization of the Ischemic Hindlimb Is Mediated by Angiopoietin-2
por: Lekas, Michael, et al.
Publicado: (2012)

The renal angiopoietin/Tie2 system in lethal human sepsis
por: Aslan, Adnan, et al.
Publicado: (2014)

Designed angiopoietin-1 variant, COMP-angiopoietin-1, rescues erectile function through healthy cavernous angiogenesis in a hypercholesterolemic mouse
por: Ryu, Ji-Kan, et al.
Publicado: (2015)

Intra and extravascular transmembrane signalling of angiopoietin-1-Tie2 receptor in health and disease
por: Makinde, T, et al.
Publicado: (2008)

Fibulin-5 Regulates Angiopoietin-1/Tie-2 Receptor Signaling in Endothelial Cells
por: Chan, Wilson, et al.
Publicado: (2016)

Angiopoietin-2, Angiopoietin-1 and subclinical cardiovascular disease in Chronic Kidney Disease
por: Tsai, Yi-Chun, et al.
Publicado: (2016)

Angiopoietin-Like Proteins in Angiogenesis, Inflammation and Cancer
por: Carbone, Carmine, et al.
Publicado: (2018)

Expression and regulation of Angiopoietins and their receptor Tie-2 in sika deer antler
por: Zhang, Hong-Liang, et al.
Publicado: (2017)

Angiopoietin-Tie Signaling Pathway in Endothelial Cells: A Computational Model
por: Zhang, Yu, et al.
Publicado: (2019)

Targeting the Angiopoietin/Tie Pathway: Prospects for Treatment of Retinal and Respiratory Disorders
por: Akwii, Racheal Grace, et al.
Publicado: (2021)

All-trans retinoic acid suppresses the angiopoietin-Tie2 pathway and inhibits angiogenesis and metastasis in esophageal squamous cell carcinoma
por: Li, Na, et al.
Publicado: (2017)

Anti-angiogenic Targets: Angiopoietin and Angiopoietin Receptors
por: Kiss, Elina A., et al.
Publicado: (2019)

Angiopoietin-2 and Angiopoietin-2/Angiopoietin-1 Ratio as Indicators of Potential Severity of Plasmodium vivax Malaria in Patients with Thrombocytopenia
por: Gomes, Luciano Teixeira, et al.
Publicado: (2014)

Multiple angiopoietin recombinant proteins activate the Tie1 receptor tyrosine kinase and promote its interaction with Tie2
por: Saharinen, Pipsa, et al.
Publicado: (2005)

Differential response of lymphatic, venous and arterial endothelial cells to angiopoietin-1 and angiopoietin-2
por: Nguyen, Vicky PKH, et al.
Publicado: (2007)

Clinical and prognostic significance of circulating levels of angiopoietin-1 and angiopoietin-2 in hepatocellular carcinoma
por: Pestana, Roberto Carmagnani, et al.
Publicado: (2018)

Angiopoietin-1, Angiopoietin-2 and Bicarbonate as Diagnostic Biomarkers in Children with Severe Sepsis
por: Wang, Kun, et al.
Publicado: (2014)

Correction: Angiopoietin-2 and Angiopoietin-2/Angiopoietin-1 Ratio as Indicators of Potential Severity of Plasmodium vivax Malaria in Patients with Thrombocytopenia
Publicado: (2015)

Angiopoietin2 and Tie2: Tied to Lymphangiogenesis and Lung Metastasis. New Perspectives in Antimetastatic Antiangiogenic Therapy
por: Albini, Adriana, et al.
Publicado: (2012)

4427 Angiopoietin F-domain valency determines outcome of Tie2 receptor engagement and accelerates angiogenesis in tissue regeneration
por: Zhao, Yan Ting, et al.
Publicado: (2020)

Regulation of Angiopoietin Signalling by Soluble Tie2 Ectodomain and Engineered Ligand Trap
por: Alawo, Deborah O. A., et al.
Publicado: (2017)

Angiopoietin-2/angiopoietin-1 as non-invasive biomarker of cirrhosis in chronic hepatitis C
por: Hernández-Bartolomé, Ángel, et al.
Publicado: (2016)

Timing and expression of the angiopoietin-1–Tie-2 pathway in murine lung development and congenital diaphragmatic hernia
por: Grzenda, Adrienne, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_l48q3ubprlgiv55gntp0sih5oe