Preventive Intrathecal Injection of Bupivacaine Alleviated Microglia Activation and Neuropathic Pain in a Rat Model of Chronic Constriction Injury

Spinal microglia are crucial to neuronal hyper-excitability and pain hypersensitivity. The local anesthetic bupivacaine is commonly used for both peripheral and spinal anesthesia. The pain-relief effects resulting from the peripheral and systemic administration of bupivacaine have been previously re...

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Detalles Bibliográficos
Autores principales: Wu, Chih-Cheng, Chang, Cheng-Yi, Tzeng, Chung-Yuh, Huang, Jen-Hsuan, Hung, Chih-Jen, Chen, Wen-Ying, Liao, Su-Lan, Kuan, Yu-Hsiang, Chen, Chun-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266705/
https://www.ncbi.nlm.nih.gov/pubmed/35806200
http://dx.doi.org/10.3390/ijms23137197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266705/
https://www.ncbi.nlm.nih.gov/pubmed/35806200
http://dx.doi.org/10.3390/ijms23137197

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