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Per1/Per2 Disruption Reduces Testosterone Synthesis and Impairs Fertility in Elderly Male Mice

Circadian rhythm disorders caused by genetic or environmental factors lead to decreased male fertility but the mechanisms are poorly understood. The current study reports that the mechanism of Per1/Per2 Double knockout (DKO) reduced the reproductive capacity of elderly male mice. The sperm motility...

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Detalles Bibliográficos
Autores principales: Liu, Qinrui, Wang, Hu, Wang, Hualin, Li, Na, He, Ruyi, Liu, Zhiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266724/
https://www.ncbi.nlm.nih.gov/pubmed/35806403
http://dx.doi.org/10.3390/ijms23137399