Vascular Dysfunction Is Central to Alzheimer’s Disease Pathogenesis in APOE e4 Carriers

Alzheimer’s disease (AD) is the most common form of dementia and the leading risk factor, after age, is possession of the apolipoprotein E epsilon 4 allele (APOE4). Approximately 50% of AD patients carry one or two copies of APOE4 but the mechanisms by which it confers risk are still unknown. APOE4...

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Detalles Bibliográficos
Autores principales: McCorkindale, Andrew N., Mundell, Hamish D., Guennewig, Boris, Sutherland, Greg T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266739/
https://www.ncbi.nlm.nih.gov/pubmed/35806110
http://dx.doi.org/10.3390/ijms23137106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266739/
https://www.ncbi.nlm.nih.gov/pubmed/35806110
http://dx.doi.org/10.3390/ijms23137106

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