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Vascular Dysfunction Is Central to Alzheimer’s Disease Pathogenesis in APOE e4 Carriers
Alzheimer’s disease (AD) is the most common form of dementia and the leading risk factor, after age, is possession of the apolipoprotein E epsilon 4 allele (APOE4). Approximately 50% of AD patients carry one or two copies of APOE4 but the mechanisms by which it confers risk are still unknown. APOE4...
Autores principales: | McCorkindale, Andrew N., Mundell, Hamish D., Guennewig, Boris, Sutherland, Greg T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266739/ https://www.ncbi.nlm.nih.gov/pubmed/35806110 http://dx.doi.org/10.3390/ijms23137106 |
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