Blocking of SGLT2 to Eliminate NADPH-Induced Oxidative Stress in Lenses of Animals with Fructose-Induced Diabetes Mellitus

Chronic hyperglycemia triggers an abnormal rise in reactive oxygen species (ROS) that leads to blindness in patients with diabetes mellitus (DM) and cataracts. In this study, the effects of dapagliflozin, metformin and resveratrol on ROS production were investigated in lens epithelial cells (LECs) o...

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Detalles Bibliográficos
Autores principales: Chen, Ying-Ying, Wu, Tsung-Tien, Ho, Chiu-Yi, Yeh, Tung-Chen, Sun, Gwo-Ching, Tseng, Ching-Jiunn, Cheng, Pei-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266761/
https://www.ncbi.nlm.nih.gov/pubmed/35806147
http://dx.doi.org/10.3390/ijms23137142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266761/
https://www.ncbi.nlm.nih.gov/pubmed/35806147
http://dx.doi.org/10.3390/ijms23137142

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