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Extracellular Cysteines Are Critical to Form Functional Cx46 Hemichannels

Connexin (Cxs) hemichannels participate in several physiological and pathological processes, but the molecular mechanisms that control their gating remain elusive. We aimed at determining the role of extracellular cysteines (Cys) in the gating and function of Cx46 hemichannels. We studied Cx46 and m...

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Detalles Bibliográficos
Autores principales: Fernández-Olivares, Ainoa, Durán-Jara, Eduardo, Verdugo, Daniel A., Fiori, Mariana C., Altenberg, Guillermo A., Stehberg, Jimmy, Alfaro, Iván, Calderón, Juan Francisco, Retamal, Mauricio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266770/
https://www.ncbi.nlm.nih.gov/pubmed/35806258
http://dx.doi.org/10.3390/ijms23137252