Impact of the Histidine-Triazole and Tryptophan-Pyrene Exchange in the WHW Peptide: Cu(II) Binding, DNA/RNA Interactions and Bioactivity

In three novel peptidoids based on the tryptophan—histidine—tryptophan (WHW) peptide, the central histidine was replaced by Ala-(triazole), and two derivatives also had one tryptophan replaced with pyrene-alkyls of different lengths and flexibility. Pyrene analogues show strong fluorescence at 480–5...

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Detalles Bibliográficos
Autores principales: Krošl, Ivona, Košćak, Marta, Ribičić, Karla, Žinić, Biserka, Majhen, Dragomira, Božinović, Ksenija, Piantanida, Ivo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266797/
https://www.ncbi.nlm.nih.gov/pubmed/35806009
http://dx.doi.org/10.3390/ijms23137006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266797/
https://www.ncbi.nlm.nih.gov/pubmed/35806009
http://dx.doi.org/10.3390/ijms23137006

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